HitPredict

Interactor 1: CK5P2 (Q96SN8)
CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215)
Gene: CDK5RAP2

Interactor 2: CP250 (Q9BV73)
Centrosome-associated protein CEP250 (250 kDa centrosomal protein) (Cep250) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Centrosomal protein 2)
Gene: CEP250

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35709258
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005829 - cytosol GO:0048471 - perinuclear region of cytoplasm GO:0070062 - extracellular exosome
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1893 Hs			1 2442
+	Hs
		724994 MYH9_HUMAN (1076-1870): 2.72e-24: 114: 10.17		CP250_HUMAN (1-2442): 2.19e-172: 592: 100.00
+	Hs
		1302317 CK5P2_HUMAN (1-1893): 4.16e-171: 572: 100.00		AKAP9_HUMAN (2-1515): 4.1e-26: 120: 11.62
+	Hs
		828618 CK5P2_HUMAN (1-1893): 4.16e-171: 572: 100.00		CENPF_HUMAN (1746-2440): 6.7e-19: 96.9: 11.02
+	Hs
		1137104 CK5P2_HUMAN (1-1893): 4.16e-171: 572: 100.00		CROCC_HUMAN (17-411): 9.1e-10: 66.9: 10.78
+	Hs
		149191 CK5P2_HUMAN (1-1893): 4.16e-171: 572: 100.00		CTRO_HUMAN (633-1361): 7.89e-09: 63.5: 21.55
+	Hs
		1034574 GOGA4_HUMAN (1-1777): 1.29e-60: 233: 10.50		GOGA4_HUMAN (3-1824): 1.71e-65: 250: 11.17
+	Hs
		1034577 GOGA4_HUMAN (1-1777): 1.29e-60: 233: 10.50		GOGB1_HUMAN (1634-2442): 3.53e-19: 97.7: 11.58
+	Hs
		148769 GOGA4_HUMAN (1-1777): 1.29e-60: 233: 10.50		CTRO_HUMAN (633-1361): 7.89e-09: 63.5: 21.55
+	Hs
		724839 MYH9_HUMAN (1076-1870): 2.72e-24: 114: 10.17		PLEC_HUMAN (3-1489): 1.72e-44: 181: 13.02
+	Hs
		528435 MYH8_HUMAN (923-1875): 1.35e-32: 141: 11.98		MYH4_HUMAN (1-882): 5.16e-36: 153: 14.25
+	Hs
		1068562 MYOME_HUMAN (50-1479): 6.18e-23: 109: 11.47		PLEC_HUMAN (3-1489): 1.72e-44: 181: 13.02
+	Hs
		1059212 GOGB1_HUMAN (1-1241): 3.09e-44: 180: 9.91		GOGB1_HUMAN (1634-2442): 3.53e-19: 97.7: 11.58
+	Hs
		724687 MYH9_HUMAN (1076-1870): 2.72e-24: 114: 10.17		MYH10_HUMAN (1424-2376): 3.63e-37: 157: 13.43
+	Hs
		1138306 MYOME_HUMAN (50-1479): 6.18e-23: 109: 11.47		AKAP9_HUMAN (2-1515): 4.1e-26: 120: 11.62
+	Hs
		528432 MYH8_HUMAN (923-1875): 1.35e-32: 141: 11.98		MYH13_HUMAN (27-621): 4.59e-10: 67.8: 13.95
+	Hs
		148338 TPR_HUMAN (1-749): 1.76e-27: 124: 10.95		CTRO_HUMAN (633-1361): 7.89e-09: 63.5: 21.55
+	Hs
		148359 DESP_HUMAN (35-576): 3.93e-27: 123: 16.16		CTRO_HUMAN (633-1361): 7.89e-09: 63.5: 21.55
+	Hs
		724943 MYH9_HUMAN (1076-1870): 2.72e-24: 114: 10.17		MY18A_HUMAN (1737-2312): 8.46e-11: 70.1: 21.19
+	Hs
		148460 MYH9_HUMAN (1076-1870): 2.72e-24: 114: 10.17		CTRO_HUMAN (633-1361): 7.89e-09: 63.5: 21.55