HitPredict

Interactor 1: SIN3A (Q96ST3)
Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a)
Gene: SIN3A

Interactor 2: KLF16 (Q9BXK1)
Krueppel-like factor 16 (Basic transcription element-binding protein 4) (BTE-binding protein 4) (Novel Sp1-like zinc finger transcription factor 2) (Transcription factor BTEB4) (Transcription factor NSLP2)
Gene: KLF16

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.696

Property	Details
Experiments	11438660, 12036432, 35140242, 22203677
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1273 Hs			1 252
+	Mm
		1141061 SIN3A_MOUSE (1-1273): 0: 1542: 98.04		KLF13_MOUSE (3-247): 1.56e-62: 199: 42.01
+	Hs
		1302481 SIN3A_HUMAN (1-1273): 0: 1545: 100.00		KLF13_HUMAN (3-247): 1.91e-61: 196: 41.81
+	Hs
		1046653 SIN3A_HUMAN (1-1273): 0: 1545: 100.00		KLF9_HUMAN (102-219): 1.1e-38: 136: 57.14
+	Hs
		158009 SIN3A_HUMAN (1-1273): 0: 1545: 100.00		KLF11_HUMAN (125-209): 7.72e-33: 126: 72.94
+	Hs
		1024877 SIN3A_HUMAN (1-1273): 0: 1545: 100.00		KLF10_HUMAN (58-209): 2.95e-32: 124: 47.47
+	Mm
		250995 SIN3A_MOUSE (1-1273): 0: 1542: 98.04		SP3_MOUSE (125-209): 1.9e-32: 126: 65.88
+	Hs
		435159 SIN3A_HUMAN (1-1273): 0: 1545: 100.00		SP1_HUMAN (111-209): 1.27e-28: 115: 58.59
+	Hs
		1032224 SIN3A_HUMAN (1-1273): 0: 1545: 100.00		KLF1_HUMAN (67-209): 3.69e-26: 106: 48.95
+	Hs
		257826 SIN3B_HUMAN (20-331): 1.12e-13: 78.4: 16.15		KLF16_HUMAN (1-235): 9.9e-76: 231: 100.00
+	Hs
		257780 SIN3B_HUMAN (20-331): 1.12e-13: 78.4: 16.15		KLF9_HUMAN (102-219): 1.1e-38: 136: 57.14