HitPredict

Interactor 1: SIN3A (Q96ST3)
Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a)
Gene: SIN3A

Interactor 2: SDS3 (Q9H7L9)
Sin3 histone deacetylase corepressor complex component SDS3 (45 kDa Sin3-associated polypeptide) (Suppressor of defective silencing 3 protein homolog)
Gene: SUDS3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.60 0.749

The method score is based on:

Property Details
Experiments 26186194, 28514442, 12724404, 11909966, 24981860, 33961781, 33283408
Identification Methods affinity chromatography technology, two hybrid, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0030336 - negative regulation of cell migration
GO:0030512 - negative regulation of transforming growth factor beta receptor signaling pathway
and 4 others

more...
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 1273
Hs

1 328
+ Hs
+ Mm
+ Hs
+ Mm
+ Dm
+ Hs
+ Dm
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+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024