HitPredict

Interactor 1: OSBL9 (Q96SU4)
Oxysterol-binding protein-related protein 9 (ORP-9) (OSBP-related protein 9)
Gene: OSBPL9

Interactor 2: VAPA (Q9P0L0)
Vesicle-associated membrane protein-associated protein A (VAMP-A) (VAMP-associated protein A) (VAP-A) (33 kDa VAMP-associated protein) (VAP-33)
Gene: VAPA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.60	0.737

Property	Details
Experiments	26496610, 28514442, 33961781, 35271311, 19615732, 25681634
Identification Methods	affinity chromatography technology, bimolecular fluorescence complementation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 736 Hs			1 249
+	Hs
		310768 OSBL9_HUMAN (1-736): 0: 723: 100.00		VAPB_HUMAN (8-249): 3.73e-83: 250: 63.12
+	Hs
		1315200 OSB10_HUMAN (3-730): 0: 545: 35.26		VAPA_HUMAN (1-249): 4.22e-100: 293: 100.00
+	Hs
		1315187 OSB11_HUMAN (7-729): 0: 540: 36.54		VAPA_HUMAN (1-249): 4.22e-100: 293: 100.00
+	Hs
		1318032 OSBL6_HUMAN (2-735): 1.19e-171: 518: 16.34		VAPA_HUMAN (1-249): 4.22e-100: 293: 100.00
+	Hs
		1331232 OSBL3_HUMAN (2-735): 2.37e-169: 511: 16.22		VAPA_HUMAN (1-249): 4.22e-100: 293: 100.00
+	Hs
		1315823 OSBL1_HUMAN (3-733): 6.57e-168: 509: 21.05		VAPA_HUMAN (1-249): 4.22e-100: 293: 100.00
+	Hs
		310785 OSB10_HUMAN (3-730): 0: 545: 35.26		VAPB_HUMAN (8-249): 3.73e-83: 250: 63.12
+	Rn
		1225298 OSBL1_RAT (6-733): 1.57e-164: 500: 20.63		VAPA_RAT (1-249): 3.22e-99: 291: 96.79
+	Hs
		310784 OSB11_HUMAN (7-729): 0: 540: 36.54		VAPB_HUMAN (8-249): 3.73e-83: 250: 63.12
+	Hs
		1318024 OSBL7_HUMAN (1-732): 2.15e-163: 494: 16.87		VAPA_HUMAN (1-249): 4.22e-100: 293: 100.00
+	Hs
		1282120 OSBP2_HUMAN (6-731): 9.12e-160: 487: 16.98		VAPA_HUMAN (1-249): 4.22e-100: 293: 100.00
+	Hs
		310792 OSBL6_HUMAN (2-735): 1.19e-171: 518: 16.34		VAPB_HUMAN (8-249): 3.73e-83: 250: 63.12
+	Hs
		310813 OSBL3_HUMAN (2-735): 2.37e-169: 511: 16.22		VAPB_HUMAN (8-249): 3.73e-83: 250: 63.12
+	Hs
		310786 OSBL1_HUMAN (3-733): 6.57e-168: 509: 21.05		VAPB_HUMAN (8-249): 3.73e-83: 250: 63.12
+	Hs
		310745 OSBP2_HUMAN (6-731): 9.12e-160: 487: 16.98		VAPB_HUMAN (8-249): 3.73e-83: 250: 63.12
+	Hs
		310506 OSBP1_HUMAN (5-731): 2.78e-151: 462: 18.82		VAPB_HUMAN (8-249): 3.73e-83: 250: 63.12
+	At
		1258327 ORP2A_ARATH (2-732): 3.35e-154: 466: 17.50		VAP11_ARATH (8-214): 4.22e-67: 210: 25.11
+	Dm
		1362486 Q9VC05_DROME (3-733): 1.17e-161: 488: 19.38		Q9W4N8_DROME (15-216): 1.28e-52: 173: 37.56
+	Hs
		1245667 OSBL1_HUMAN (3-733): 6.57e-168: 509: 21.05		MSPD2_HUMAN (14-190): 1.24e-39: 144: 19.34
+	Dm
		1362484 Q9VC05_DROME (3-733): 1.17e-161: 488: 19.38		Q9VSD3_DROME (11-201): 1.14e-46: 156: 29.02