Interactor 1: PGRC1 (O00264)
Membrane-associated progesterone receptor component 1 (mPR) (Dap1) (IZA)
Gene: PGRMC1

Interactor 2: DHCR7 (Q9UBM7)
7-dehydrocholesterol reductase (7-DHC reductase) (EC 1.3.1.21) (Cholesterol-5,6-epoxide hydrolase subunit DHCR7) (EC 3.3.2.11) (Delta7-sterol reductase) (Sterol Delta(7)-reductase) (Sterol reductase SR-2)
Gene: DHCR7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 0.60 0.611

The method score is based on:

Property Details
Experiments 35271311, 40437099
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0016020 - membrane
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 195
Hs

1 475
+ Hs
+ Hs

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Last updated: 11Aug2025