Interactor 1: UHRF1 (Q96T88)
E3 ubiquitin-protein ligase UHRF1 (EC 2.3.2.27) (Inverted CCAAT box-binding protein of 90 kDa) (Nuclear protein 95) (Nuclear zinc finger protein Np95) (HuNp95) (hNp95) (RING finger protein 106) (RING-type E3 ubiquitin transferase UHRF1) (Transcription factor ICBP90) (Ubiquitin-like PHD and RING finger domain-containing protein 1) (hUHRF1) (Ubiquitin-like-containing PHD and RING finger domains protein 1)
Gene: UHRF1

Interactor 2: FACD2 (Q9BXW9)
Fanconi anemia group D2 protein (Protein FACD2)
Gene: FANCD2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 1.00 0.806

The method score is based on:

Property Details
Experiments 30335751, 31180492
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains FancD2~ubiquitin
Common GO terms GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 793
Hs

1 1451
+ Hs
+ Hs
+ Mm
+ Mm
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024