HitPredict

Interactor 1: UHRF1 (Q96T88)
E3 ubiquitin-protein ligase UHRF1 (EC 2.3.2.27) (Inverted CCAAT box-binding protein of 90 kDa) (Nuclear protein 95) (Nuclear zinc finger protein Np95) (HuNp95) (hNp95) (RING finger protein 106) (RING-type E3 ubiquitin transferase UHRF1) (Transcription factor ICBP90) (Ubiquitin-like PHD and RING finger domain-containing protein 1) (hUHRF1) (Ubiquitin-like-containing PHD and RING finger domains protein 1)
Gene: UHRF1

Interactor 2: DNM3B (Q9UBC3)
DNA (cytosine-5)-methyltransferase 3B (Dnmt3b) (EC 2.1.1.37) (DNA methyltransferase HsaIIIB) (DNA MTase HsaIIIB) (M.HsaIIIB)
Gene: DNMT3B

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 0.60 0.661

The method score is based on:

Property Details
Experiments 19798101, 36458887, 22064703
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, fluorescence technology, anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 793
Hs

1 853
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
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+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024