Interactor 1: YMEL1 (Q96TA2)
ATP-dependent zinc metalloprotease YME1L1 (EC 3.4.24.-) (EC 3.6.-.-) (ATP-dependent metalloprotease FtsH1) (Meg-4) (Presenilin-associated metalloprotease) (PAMP) (YME1-like protein 1)
Gene: YME1L1

Interactor 2: CLPB (Q9H078)
Mitochondrial disaggregase (EC 3.6.1.-) (Suppressor of potassium transport defect 3) [Cleaved into: Mitochondrial disaggregase, cleaved form]
Gene: CLPB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 31617661
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~AAA_2, AAA~ClpB_D2-small, AAA_lid_3~Ank_2
Common GO terms GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0016887 - ATP hydrolysis activity
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 773
Hs

1 707
+ Hs
+ Sc
+ Sc
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024