HitPredict

Interactor 1: CYH2 (Q99418)
Cytohesin-2 (ARF exchange factor) (ARF nucleotide-binding site opener) (Protein ARNO) (PH, SEC7 and coiled-coil domain-containing protein 2)
Gene: CYTH2

Interactor 2: VPP2 (Q9Y487)
V-type proton ATPase 116 kDa subunit a 2 (V-ATPase 116 kDa subunit a 2) (Lysosomal H(+)-transporting ATPase V0 subunit a 2) (TJ6) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2)
Gene: ATP6V0A2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	21307348, 16415858
Identification Methods	pull down, anti bait coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000139 - Golgi membrane GO:0005886 - plasma membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 400 Hs			1 856
+	Mm
		551461 CYH2_MOUSE (1-400): 9.2e-180: 507: 99.25		VPP2_MOUSE (1-856): 0: 1294: 91.59
+	Hs
		1274133 CYH2_HUMAN (1-400): 2.27e-180: 509: 100.00		VPP1_HUMAN (1-842): 0: 1278: 53.19
+	Hs
		1303450 CYH2_HUMAN (1-400): 2.27e-180: 509: 100.00		VPP4_HUMAN (1-843): 0: 1227: 51.89
+	Hs
		1035683 CYH2_HUMAN (1-400): 2.27e-180: 509: 100.00		VPP3_HUMAN (1-843): 0: 1082: 49.35