HitPredict

Interactor 1: NP1L3 (Q99457)
Nucleosome assembly protein 1-like 3
Gene: NAP1L3

Interactor 2: TSYL1 (Q9H0U9)
Testis-specific Y-encoded-like protein 1 (TSPY-like protein 1)
Gene: TSPYL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	NAP~NAP
Common GO terms	GO:0000785 - chromatin GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0006334 - nucleosome assembly GO:0042393 - histone binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 506 Hs			1 437
+	Hs
		1303679 NP1L3_HUMAN (1-506): 8.26e-151: 442: 100.00		TSYL4_HUMAN (1-437): 2.62e-163: 467: 52.02
+	Hs
		1223686 Q8IYV1_HUMAN (1-506): 1.5e-150: 441: 99.61		TSYL4_HUMAN (1-437): 2.62e-163: 467: 52.02
+	Hs
		1328221 NP1L2_HUMAN (197-493): 1.63e-76: 249: 34.78		TSYL1_HUMAN (1-437): 0: 540: 100.00
+	Hs
		1328217 TSYL4_HUMAN (176-487): 7.52e-71: 233: 19.17		TSYL1_HUMAN (1-437): 0: 540: 100.00
+	Hs
		1151427 Q6FI91_HUMAN (261-485): 2.71e-61: 208: 18.22		Q6FI91_HUMAN (1-437): 0: 542: 99.09
+	Hs
		1328205 TSYL1_HUMAN (261-485): 6.89e-62: 210: 18.22		TSYL1_HUMAN (1-437): 0: 540: 100.00
+	Hs
		1355917 NP1L2_HUMAN (197-493): 1.63e-76: 249: 34.78		TSYL4_HUMAN (1-437): 2.62e-163: 467: 52.02
+	Hs
		1237381 TSYL6_HUMAN (169-485): 6.43e-62: 210: 16.72		TSYL2_HUMAN (38-420): 1.14e-109: 340: 37.98
+	Hs
		1328206 TSYL1_HUMAN (261-485): 6.89e-62: 210: 18.22		TSYL2_HUMAN (38-420): 1.14e-109: 340: 37.98
+	Hs
		1151432 Q6FI91_HUMAN (261-485): 2.71e-61: 208: 18.22		TSYL2_HUMAN (38-420): 1.14e-109: 340: 37.98
+	Hs
		63699 TSYL4_HUMAN (176-487): 7.52e-71: 233: 19.17		TSPY2_HUMAN (135-429): 3.07e-95: 290: 36.95
+	Hs
		965385 TSYL5_HUMAN (194-485): 4.74e-62: 210: 17.75		TSPY1_HUMAN (135-429): 6.88e-94: 287: 37.29
+	Hs
		963900 TSYL1_HUMAN (261-485): 6.89e-62: 210: 18.22		SET_HUMAN (185-411): 1.21e-89: 275: 31.78
+	Hs
		876924 NP1L2_HUMAN (197-493): 1.63e-76: 249: 34.78		NP1L1_HUMAN (188-408): 3.64e-72: 233: 17.15
+	Hs
		1306101 TSYL4_HUMAN (176-487): 7.52e-71: 233: 19.17		NP1L4_HUMAN (172-408): 1.06e-74: 240: 15.50
+	Hs
		963791 SET_HUMAN (209-485): 1.87e-58: 196: 18.21		SET_HUMAN (185-411): 1.21e-89: 275: 31.78
+	Hs
		483599 SET_HUMAN (209-485): 1.87e-58: 196: 18.21		SETLP_HUMAN (185-412): 8.67e-85: 263: 31.22
+	Pf
		1211854 Q8I608_PLAF7 (220-494): 1.9e-69: 227: 22.15		Q8I608_PLAF7 (186-409): 3.24e-69: 225: 19.00