Interactor 1: CDC5L (Q99459)
Cell division cycle 5-like protein (Cdc5-like protein) (Pombe cdc5-related protein)
Gene: CDC5L

Interactor 2: PRP19 (Q9UMS4)
Pre-mRNA-processing factor 19 (EC 2.3.2.27) (Nuclear matrix protein 200) (PRP19/PSO4 homolog) (hPso4) (RING-type E3 ubiquitin transferase PRP19) (Senescence evasion factor)
Gene: PRPF19

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.981

The method score is based on:

Property Details
Experiments 28514442, 28666352, 29395067, 32460013, 33961781, 35271311, 20176811, 20467437, 11101529, 20595234, 17276391, 19633697
Identification Methods affinity chromatography technology, proximity labelling technology, far western blotting, biochemical, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Myb_Cef~Prp19
Common GO terms GO:0000077 - DNA damage checkpoint signaling
GO:0000398 - mRNA splicing, via spliceosome
GO:0000974 - Prp19 complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 6 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 802
Hs

1 504
+ Hs
+ Hs
+ Hs
+ Dm
+ At
+ Mm
+ Hs
+ Hs
+ Sc
+ Hs

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Last updated: 15 Jul 2024