HitPredict

Interactor 1: CDC5L (Q99459)
Cell division cycle 5-like protein (Cdc5-like protein) (Pombe cdc5-related protein)
Gene: CDC5L

Interactor 2: TTF2 (Q9UNY4)
Transcription termination factor 2 (EC 3.6.4.-) (Lodestar homolog) (RNA polymerase II termination factor) (Transcription release factor 2) (F2) (HuF2)
Gene: TTF2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.644

Property	Details
Experiments	12927788, 20467437
Identification Methods	two hybrid, affinity chromatography technology, anti bait coimmunoprecipitation, chromatography technology
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005681 - spliceosomal complex GO:0006281 - DNA repair
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 802 Hs			1 1162
+	Hs
		1018654 CDC5L_HUMAN (1-802): 0: 756: 100.00		CHD3_HUMAN (170-1160): 0: 613: 15.72
+	Hs
		1303767 CDC5L_HUMAN (1-802): 0: 756: 100.00		Q9HBD4_HUMAN (113-1159): 0: 595: 17.27
+	Hs
		847061 CDC5L_HUMAN (1-802): 0: 756: 100.00		SMCA4_HUMAN (113-1159): 0: 593: 17.27
+	Hs
		1303772 CDC5L_HUMAN (1-802): 0: 756: 100.00		CHD8_HUMAN (93-1160): 2.85e-177: 579: 15.22
+	Hs
		1059816 CDC5L_HUMAN (1-802): 0: 756: 100.00		CHD4_HUMAN (172-1160): 3.82e-178: 573: 15.46
+	Hs
		846855 CDC5L_HUMAN (1-802): 0: 756: 100.00		SMCA2_HUMAN (117-1159): 1.87e-177: 565: 16.00
+	Hs
		229472 CDC5L_HUMAN (1-802): 0: 756: 100.00		SMCA5_HUMAN (452-1162): 1.14e-175: 546: 20.03
+	Hs
		1303786 CDC5L_HUMAN (1-802): 0: 756: 100.00		HELLS_HUMAN (378-1160): 8.61e-176: 540: 18.30
+	Hs
		486981 MYBB_HUMAN (4-527): 1.91e-47: 182: 16.51		TTF2_HUMAN (1-1162): 0: 923: 100.00
+	Hs
		1055156 CDC5L_HUMAN (1-802): 0: 756: 100.00		HLTF_HUMAN (618-1137): 2.01e-68: 251: 30.52
+	Hs
		163637 CDC5L_HUMAN (1-802): 0: 756: 100.00		BTAF1_HUMAN (563-1160): 1.99e-41: 168: 27.38
+	Hs
		1102058 CDC5L_HUMAN (1-802): 0: 756: 100.00		ERC6L_HUMAN (570-1162): 9.47e-37: 153: 26.75
+	Hs
		486936 MYBB_HUMAN (4-527): 1.91e-47: 182: 16.51		CHD5_HUMAN (114-1160): 0: 614: 15.32
+	Hs
		486903 MYBB_HUMAN (4-527): 1.91e-47: 182: 16.51		CHD3_HUMAN (170-1160): 0: 613: 15.72
+	Hs
		486910 MYBB_HUMAN (4-527): 1.91e-47: 182: 16.51		CHD4_HUMAN (172-1160): 3.82e-178: 573: 15.46
+	Hs
		486780 MYB_HUMAN (398-727): 5.82e-27: 119: 12.06		CHD3_HUMAN (170-1160): 0: 613: 15.72
+	Hs
		229287 MYBB_HUMAN (4-527): 1.91e-47: 182: 16.51		SMCA5_HUMAN (452-1162): 1.14e-175: 546: 20.03
+	Hs
		486872 MYBB_HUMAN (4-527): 1.91e-47: 182: 16.51		SMCA1_HUMAN (453-1159): 1.32e-167: 525: 21.75
+	Hs
		486837 MYB_HUMAN (398-727): 5.82e-27: 119: 12.06		CHD7_HUMAN (93-1160): 9.11e-179: 585: 15.23
+	Hs
		486760 MYB_HUMAN (398-727): 5.82e-27: 119: 12.06		SMCA2_HUMAN (117-1159): 1.87e-177: 565: 16.00