HitPredict

Interactor 1: CDC5L (Q99459)
Cell division cycle 5-like protein (Cdc5-like protein) (Pombe cdc5-related protein)
Gene: CDC5L

Interactor 2: MACF1 (Q9UPN3)
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 (620 kDa actin-binding protein) (ABP620) (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha)
Gene: MACF1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.614

Property	Details
Experiments	20467437, 17043677
Identification Methods	affinity chromatography technology, two hybrid, anti bait coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005737 - cytoplasm GO:0016020 - membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 802 Hs			1 7388
+	Hs
		885299 CDC5L_HUMAN (1-802): 0: 756: 100.00		EPIPL_HUMAN (1538-2789): 1.49e-35: 154: 13.15
+	Hs
		1068641 CDC5L_HUMAN (1-802): 0: 756: 100.00		PLEC_HUMAN (2677-3656): 8.53e-27: 124: 8.13
+	Hs
		551813 CDC5L_HUMAN (1-802): 0: 756: 100.00		DESP_HUMAN (2737-3775): 9.21e-27: 124: 8.65
+	Hs
		1244128 CDC5L_HUMAN (1-802): 0: 756: 100.00		SYNE1_HUMAN (343-1742): 3.05e-13: 80.2: 8.97
+	Hs
		974135 CDC5L_HUMAN (1-802): 0: 756: 100.00		DYST_HUMAN (478-1511): 2.31e-12: 77.1: 9.72
+	Hs
		963400 CDC5L_HUMAN (1-802): 0: 756: 100.00		SPTB2_HUMAN (6378-7134): 6.05e-11: 72.5: 13.80
+	Hs
		1059259 CDC5L_HUMAN (1-802): 0: 756: 100.00		GOGB1_HUMAN (6684-7219): 2.29e-10: 70.5: 9.23
+	Hs
		1045493 CDC5L_HUMAN (1-802): 0: 756: 100.00		SPTN1_HUMAN (433-1344): 7.43e-10: 68.8: 13.39
+	Hs
		486891 MYBB_HUMAN (4-527): 1.91e-47: 182: 16.51		SPTB2_HUMAN (6378-7134): 6.05e-11: 72.5: 13.80
+	Hs
		486785 MYB_HUMAN (398-727): 5.82e-27: 119: 12.06		SPTN1_HUMAN (433-1344): 7.43e-10: 68.8: 13.39