HitPredict

Interactor 1: CDC5L (Q99459)
Cell division cycle 5-like protein (Cdc5-like protein) (Pombe cdc5-related protein)
Gene: CDC5L

Interactor 2: SF3B6 (Q9Y3B4)
Splicing factor 3B subunit 6 (Pre-mRNA branch site protein p14) (SF3b 14 kDa subunit) (SF3B14a) (Spliceosome-associated protein, 14-kDa) (Splicing factor 3b, subunit 6, 14kDa)
Gene: SF3B6

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	20467437, 29395067
Identification Methods	affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005681 - spliceosomal complex and 1 others more... GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 802 Hs			1 125
+	Hs
		441355 CDC5L_HUMAN (1-802): 0: 756: 100.00		RU2B_HUMAN (16-111): 5.15e-38: 129: 25.00
+	Hs
		1303859 CDC5L_HUMAN (1-802): 0: 756: 100.00		PPIE_HUMAN (17-108): 4.08e-29: 108: 22.11
+	Hs
		992897 CDC5L_HUMAN (1-802): 0: 756: 100.00		SRSF1_HUMAN (21-91): 3.36e-18: 79: 33.80
+	Hs
		1028601 CDC5L_HUMAN (1-802): 0: 756: 100.00		SRSF9_HUMAN (21-94): 4.86e-17: 75.1: 31.08
+	Hs
		446759 CDC5L_HUMAN (1-802): 0: 756: 100.00		SNRPA_HUMAN (11-93): 1.11e-10: 58.7: 22.62
+	Sp
		765715 CEF1_SCHPO (6-791): 1.23e-143: 442: 36.61		RU2B_SCHPO (19-96): 3.44e-25: 93.6: 29.27
+	At
		1322381 MYB44_ARATH (8-147): 5.78e-51: 182: 26.17		SF3B6_ARATH (1-122): 1.22e-43: 140: 63.12