HitPredict

Interactor 1: PSMD1 (Q99460)
26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1) (26S proteasome subunit p112)
Gene: PSMD1

Interactor 2: UBQL1 (Q9UMX0)
Ubiquilin-1 (Protein linking IAP with cytoskeleton 1) (PLIC-1) (hPLIC-1)
Gene: UBQLN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	27114451
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PC_rep~ubiquitin
Common GO terms	GO:0000502 - proteasome complex GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 953 Hs			1 589
+	Hs
		1303948 PSMD1_HUMAN (1-953): 0: 1310: 100.00		UBQL2_HUMAN (1-589): 9.51e-145: 433: 71.29
+	Hs
		1303937 PSMD1_HUMAN (1-953): 0: 1310: 100.00		UBQL4_HUMAN (28-589): 1.35e-135: 409: 57.64
+	Dm
		1359018 PSMD1_DROME (2-933): 0: 1114: 61.64		Q9VWD9_DROME (30-582): 3.32e-135: 407: 47.39
+	Hs
		1259550 PSMD1_HUMAN (1-953): 0: 1310: 100.00		DDI1_HUMAN (47-318): 6.39e-53: 187: 15.60
+	Hs
		1136649 PSMD1_HUMAN (1-953): 0: 1310: 100.00		DDI2_HUMAN (47-318): 2.03e-49: 178: 13.52
+	Hs
		924124 PSMD1_HUMAN (1-953): 0: 1310: 100.00		RS27A_HUMAN (37-123): 1.1e-12: 68: 30.68
+	Hs
		1027821 PSMD2_HUMAN (8-796): 0: 802: 18.73		UBQL1_HUMAN (1-589): 1.23e-174: 509: 100.00
+	Hs
		1027815 PSMD2_HUMAN (8-796): 0: 802: 18.73		UBQL2_HUMAN (1-589): 9.51e-145: 433: 71.29
+	Hs
		1027806 PSMD2_HUMAN (8-796): 0: 802: 18.73		UBQL4_HUMAN (28-589): 1.35e-135: 409: 57.64
+	Sc
		693266 RPN2_YEAST (2-953): 0: 984: 40.26		RAD23_YEAST (45-419): 1.17e-31: 128: 17.73
+	Dm
		1374998 Q9VW54_DROME (12-796): 0: 702: 16.86		Q9VWD9_DROME (30-582): 3.32e-135: 407: 47.39
+	Hs
		1027733 PSMD2_HUMAN (8-796): 0: 802: 18.73		DDI1_HUMAN (47-318): 6.39e-53: 187: 15.60
+	Hs
		1027692 PSMD2_HUMAN (8-796): 0: 802: 18.73		DDI2_HUMAN (47-318): 2.03e-49: 178: 13.52
+	Hs
		923974 PSMD2_HUMAN (8-796): 0: 802: 18.73		RS27A_HUMAN (37-123): 1.1e-12: 68: 30.68
+	Sp
		953205 RPN1_SCHPO (8-794): 0: 666: 18.03		DSK2_SCHPO (37-244): 7.16e-27: 113: 22.79
+	Sc
		697080 RPN1_YEAST (8-604): 4.59e-149: 468: 15.96		RAD23_YEAST (45-419): 1.17e-31: 128: 17.73
+	Sc
		753873 RPN1_YEAST (8-604): 4.59e-149: 468: 15.96		DSK2_YEAST (36-243): 8.16e-32: 128: 30.73