HitPredict

Interactor 1: PSMD1 (Q99460)
26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1) (26S proteasome subunit p112)
Gene: PSMD1

Interactor 2: CHIP (Q9UNE7)
E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (Antigen NY-CO-7) (CLL-associated antigen KW-8) (Carboxy terminus of Hsp70-interacting protein) (RING-type E3 ubiquitin transferase CHIP) (STIP1 homology and U box-containing protein 1)
Gene: STUB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	32723828, 16207813
Identification Methods	enzymatic study, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 953 Hs			1 303
+	Hs
		1027822 PSMD2_HUMAN (8-796): 0: 802: 18.73		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		1027771 PSMD2_HUMAN (8-796): 0: 802: 18.73		Q9BPW0_HUMAN (1-259): 2.98e-36: 137: 20.91
+	Hs
		213540 PSMD2_HUMAN (8-796): 0: 802: 18.73		SGTA_HUMAN (3-140): 2.4e-33: 126: 29.71