HitPredict

Interactor 1: NDUA4 (O00483)
Cytochrome c oxidase subunit NDUFA4 (Complex I-MLRQ) (CI-MLRQ) (NADH-ubiquinone oxidoreductase MLRQ subunit)
Gene: NDUFA4

Interactor 2: INSR (P06213)
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
Gene: INSR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0044877 - protein-containing complex binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 81 Hs			1 1382
+	Hs
		130406 NDUA4_HUMAN (1-81): 4.77e-50: 153: 100.00		IGF1R_HUMAN (31-1380): 0: 1353: 56.11
+	Hs
		130445 NDUA4_HUMAN (1-81): 4.77e-50: 153: 100.00		EPHA8_HUMAN (644-1322): 3.66e-168: 531: 20.68
+	Hs
		130410 NDUA4_HUMAN (1-81): 4.77e-50: 153: 100.00		ROS1_HUMAN (511-1377): 3.38e-158: 530: 22.63
+	Hs
		130400 NDUA4_HUMAN (1-81): 4.77e-50: 153: 100.00		ERBB2_HUMAN (978-1381): 5.36e-93: 330: 25.67
+	Hs
		130401 NDUA4_HUMAN (1-81): 4.77e-50: 153: 100.00		NTRK1_HUMAN (996-1286): 9.16e-68: 247: 42.62
+	Hs
		130507 NDUA4_HUMAN (1-81): 4.77e-50: 153: 100.00		NTRK3_HUMAN (996-1290): 1.93e-64: 238: 39.43
+	Hs
		130493 NDUA4_HUMAN (1-81): 4.77e-50: 153: 100.00		MERTK_HUMAN (835-1301): 1.61e-62: 234: 32.36
+	Hs
		130446 NDUA4_HUMAN (1-81): 4.77e-50: 153: 100.00		UFO_HUMAN (789-1294): 1.77e-61: 229: 31.09