HitPredict

Interactor 1: RING2 (Q99496)
E3 ubiquitin-protein ligase RING2 (EC 2.3.2.27) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3) (Protein DinG) (RING finger protein 1B) (RING1b) (RING finger protein 2) (RING finger protein BAP-1) (RING-type E3 ubiquitin transferase RING2)
Gene: RNF2

Interactor 2: RING2 (Q99496)
E3 ubiquitin-protein ligase RING2 (EC 2.3.2.27) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3) (Protein DinG) (RING finger protein 1B) (RING1b) (RING finger protein 2) (RING finger protein BAP-1) (RING-type E3 ubiquitin transferase RING2)
Gene: RNF2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.914

The method score is based on:

Property Details
Experiments 28073915, 18650381, 20351251, 22910419, 18616292
Identification Methods enzymatic study, affinity chromatography technology, two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains RAWUL~RAWUL, zf-C3HC4_2~zf-C3HC4_2
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000151 - ubiquitin ligase complex
GO:0000278 - mitotic cell cycle
GO:0000791 - euchromatin
GO:0001702 - gastrulation with mouth forming second
and 20 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 336
Hs

1 336
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Last updated: 15 Jul 2024