HitPredict

Interactor 1: RING2 (Q99496)
E3 ubiquitin-protein ligase RING2 (EC 2.3.2.27) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3) (Protein DinG) (RING finger protein 1B) (RING1b) (RING finger protein 2) (RING finger protein BAP-1) (RING-type E3 ubiquitin transferase RING2)
Gene: RNF2

Interactor 2: NKX31 (Q99801)
Homeobox protein Nkx-3.1 (Homeobox protein NK-3 homolog A)
Gene: NKX3-1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	27339988
Identification Methods	tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 336 Hs			1 234
+	Hs
		620193 RING2_HUMAN (1-336): 4.99e-112: 330: 100.00		PAX7_HUMAN (2-233): 1.1e-34: 131: 19.18
+	Hs
		679160 RING2_HUMAN (1-336): 4.99e-112: 330: 100.00		TLX1_HUMAN (54-221): 5.02e-36: 131: 30.18
+	Hs
		679100 RING1_HUMAN (6-336): 8.6e-69: 222: 51.24		TLX1_HUMAN (54-221): 5.02e-36: 131: 30.18
+	Hs
		211843 RING1_HUMAN (6-336): 8.6e-69: 222: 51.24		TLX3_HUMAN (112-215): 4.85e-31: 117: 40.00
+	Hs
		620197 PCGF1_HUMAN (28-336): 1.84e-47: 162: 16.88		PAX7_HUMAN (2-233): 1.1e-34: 131: 19.18
+	Hs
		679164 PCGF1_HUMAN (28-336): 1.84e-47: 162: 16.88		TLX1_HUMAN (54-221): 5.02e-36: 131: 30.18
+	Hs
		211952 PCGF1_HUMAN (28-336): 1.84e-47: 162: 16.88		TLX3_HUMAN (112-215): 4.85e-31: 117: 40.00
+	Hs
		595583 BMI1_HUMAN (34-332): 4.13e-45: 158: 15.51		HXA5_HUMAN (20-199): 2.3e-32: 120: 20.32
+	Hs
		201868 BMI1_HUMAN (34-332): 4.13e-45: 158: 15.51		HXA3_HUMAN (82-221): 7.47e-31: 119: 33.33
+	Hs
		536730 TRI27_HUMAN (36-282): 4.98e-37: 141: 16.08		PAX7_HUMAN (2-233): 1.1e-34: 131: 19.18
+	Hs
		620169 PCGF5_HUMAN (34-334): 1.89e-39: 141: 15.24		PAX7_HUMAN (2-233): 1.1e-34: 131: 19.18
+	Hs
		679129 PCGF5_HUMAN (34-334): 1.89e-39: 141: 15.24		TLX1_HUMAN (54-221): 5.02e-36: 131: 30.18
+	Hs
		211899 PCGF5_HUMAN (34-334): 1.89e-39: 141: 15.24		TLX3_HUMAN (112-215): 4.85e-31: 117: 40.00
+	Hs
		882136 PCGF5_HUMAN (34-334): 1.89e-39: 141: 15.24		GSC_HUMAN (10-207): 1.34e-30: 115: 21.61
+	Hs
		536738 TRI27_HUMAN (36-282): 4.98e-37: 141: 16.08		HXC8_HUMAN (2-192): 2.32e-30: 114: 21.65
+	Mm
		678760 BRCA1_MOUSE (36-215): 4.39e-27: 114: 23.28		HXA2_MOUSE (7-214): 6.73e-32: 121: 21.30
+	Hs
		213349 PCGF5_HUMAN (34-334): 1.89e-39: 141: 15.24		TLX2_HUMAN (114-196): 1.57e-12: 67: 48.19