HitPredict

Interactor 1: RING2 (Q99496)
E3 ubiquitin-protein ligase RING2 (EC 2.3.2.27) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3) (Protein DinG) (RING finger protein 1B) (RING1b) (RING finger protein 2) (RING finger protein BAP-1) (RING-type E3 ubiquitin transferase RING2)
Gene: RNF2

Interactor 2: FBSL (Q9HCM7)
Fibrosin-1-like protein (AUTS2-like protein) (HBV X-transactivated gene 9 protein) (HBV XAg-transactivated protein 9)
Gene: FBRSL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.50	0.599

Property	Details
Experiments	24457600, 27705803, 22325352
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 336 Hs			1 1045
+	Hs
		988026 RING1_HUMAN (6-336): 8.6e-69: 222: 51.24		FBSL_HUMAN (1-1045): 0: 1132: 100.00
+	Hs
		1108546 PCGF3_HUMAN (36-334): 3.56e-44: 153: 18.15		FBSL_HUMAN (1-1045): 0: 1132: 100.00
+	Hs
		1264228 RING2_HUMAN (1-336): 4.99e-112: 330: 100.00		AUTS2_HUMAN (71-792): 0: 728: 40.61
+	Mm
		397 RING2_MOUSE (1-336): 4.78e-112: 330: 99.70		AUTS2_MOUSE (71-782): 0: 712: 39.43
+	Hs
		987999 RING1_HUMAN (6-336): 8.6e-69: 222: 51.24		AUTS2_HUMAN (71-792): 0: 728: 40.61
+	Hs
		1108524 PCGF3_HUMAN (36-334): 3.56e-44: 153: 18.15		AUTS2_HUMAN (71-792): 0: 728: 40.61
+	Hs
		1264229 PCGF6_HUMAN (29-296): 6.61e-39: 142: 14.76		AUTS2_HUMAN (71-792): 0: 728: 40.61
+	Mm
		393 PCGF3_MOUSE (36-334): 2.33e-43: 151: 18.15		AUTS2_MOUSE (71-782): 0: 712: 39.43
+	Hs
		111280 RING2_HUMAN (1-336): 4.99e-112: 330: 100.00		J3KNZ9_HUMAN (80-794): 2.2e-96: 329: 29.52
+	Hs
		1304115 RING2_HUMAN (1-336): 4.99e-112: 330: 100.00		FBRS_HUMAN (477-794): 7.33e-82: 275: 36.73
+	Hs
		988023 RING1_HUMAN (6-336): 8.6e-69: 222: 51.24		FBRS_HUMAN (477-794): 7.33e-82: 275: 36.73
+	Hs
		1311545 PCGF1_HUMAN (28-336): 1.84e-47: 162: 16.88		FBRS_HUMAN (477-794): 7.33e-82: 275: 36.73
+	Hs
		718208 BMI1_HUMAN (34-332): 4.13e-45: 158: 15.51		FBRS_HUMAN (477-794): 7.33e-82: 275: 36.73
+	Hs
		718429 PCGF2_HUMAN (34-332): 8.08e-44: 155: 16.89		FBRS_HUMAN (477-794): 7.33e-82: 275: 36.73
+	Hs
		1108544 PCGF3_HUMAN (36-334): 3.56e-44: 153: 18.15		FBRS_HUMAN (477-794): 7.33e-82: 275: 36.73
+	Hs
		1316704 PCGF6_HUMAN (29-296): 6.61e-39: 142: 14.76		FBRS_HUMAN (477-794): 7.33e-82: 275: 36.73
+	Mm
		1161099 RING2_MOUSE (1-336): 4.78e-112: 330: 99.70		Q6PED7_MOUSE (870-1045): 4.22e-10: 65.6: 36.44
+	Mm
		193409 RING1_MOUSE (6-336): 1.23e-70: 227: 51.49		Q6PED7_MOUSE (870-1045): 4.22e-10: 65.6: 36.44
+	Mm
		1161097 PCGF3_MOUSE (36-334): 2.33e-43: 151: 18.15		Q6PED7_MOUSE (870-1045): 4.22e-10: 65.6: 36.44
+	Mm
		1112807 PCGF5_MOUSE (34-334): 1.96e-41: 146: 14.76		Q6PED7_MOUSE (870-1045): 4.22e-10: 65.6: 36.44