Interactor 1: PARK7 (Q99497)
Parkinson disease protein 7 (Maillard deglycase) (Oncogene DJ1) (Parkinsonism-associated deglycase) (Protein DJ-1) (DJ-1) (Protein/nucleic acid deglycase DJ-1) (EC 3.1.2.-, EC 3.5.1.-, EC 3.5.1.124)
Gene: PARK7

Interactor 2: PARK7 (Q99497)
Parkinson disease protein 7 (Maillard deglycase) (Oncogene DJ1) (Parkinsonism-associated deglycase) (Protein DJ-1) (DJ-1) (Protein/nucleic acid deglycase DJ-1) (EC 3.1.2.-, EC 3.5.1.-, EC 3.5.1.124)
Gene: PARK7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.985

The method score is based on:

Property Details
Experiments 29976090, 31353306, 37071682, 15525661, 15894486, 15983381, 12796482, 12855764, 14665635, 14713311, 17331951, 12761214, 20304780, 16390825, 18922803, 20156966, 12851414, 15502874, 24947010
Identification Methods affinity chromatography technology, cross-linking study, two hybrid, x-ray crystallography, fluorescent resonance energy transfer, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains DJ-1_PfpI~DJ-1_PfpI
Common GO terms GO:0000785 - chromatin
GO:0001933 - negative regulation of protein phosphorylation
GO:0002866 - positive regulation of acute inflammatory response to antigenic stimulus
GO:0003713 - transcription coactivator activity
GO:0003729 - mRNA binding
and 134 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 189
Hs

1 189
+ Rn
+ Ce
+ Sp
+ Cj
+ At

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Last updated: 15 Jul 2024