HitPredict

Interactor 1: EYA1 (Q99502)
Eyes absent homolog 1 (EC 3.1.3.16) (EC 3.1.3.48)
Gene: EYA1

Interactor 2: FZR1 (Q9UM11)
Fizzy-related protein homolog (Fzr) (CDC20-like protein 1) (Cdh1/Hct1 homolog) (hCDH1)
Gene: FZR1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23263983
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 592 Hs			1 496
+	Hs
		1281339 EYA1_HUMAN (1-592): 0: 571: 100.00		FBXW7_HUMAN (87-424): 1.7e-71: 242: 18.68
+	Hs
		1288262 EYA3_HUMAN (41-592): 1.55e-159: 470: 50.99		SNR40_HUMAN (32-339): 1.33e-49: 175: 15.89
+	Hs
		318612 EYA4_HUMAN (1-592): 8.84e-173: 506: 68.49		CDC20_HUMAN (395-494): 7.34e-10: 63: 16.67
+	Hs
		624985 RPB1_HUMAN (90-285): 4.06e-09: 61.9: 14.54		FBXW7_HUMAN (87-424): 1.7e-71: 242: 18.68
+	Hs
		124040 SPT5H_HUMAN (4-129): 1.43e-09: 63.4: 14.84		SNR40_HUMAN (32-339): 1.33e-49: 175: 15.89
+	Mm
		444958 RPB1_MOUSE (19-256): 5.92e-11: 67.7: 14.29		WDR5_MOUSE (389-496): 1.49e-26: 111: 18.35
+	Hs
		903374 KMT2C_HUMAN (21-304): 4.57e-10: 64.9: 13.84		WDR5_HUMAN (389-496): 1.49e-26: 111: 18.35
+	Hs
		903405 CBP_HUMAN (52-326): 3.34e-09: 62.2: 11.64		WDR5_HUMAN (389-496): 1.49e-26: 111: 18.35
+	Mm
		903669 KMT2C_MOUSE (9-281): 5.08e-09: 61.5: 12.14		WDR5_MOUSE (389-496): 1.49e-26: 111: 18.35
+	Hs
		560858 RPB1_HUMAN (90-285): 4.06e-09: 61.9: 14.54		GBB3_HUMAN (349-492): 2.25e-16: 82: 19.46
+	Hs
		124015 SPT5H_HUMAN (4-129): 1.43e-09: 63.4: 14.84		POC1A_HUMAN (68-215): 1.37e-12: 71.1: 10.60
+	Hs
		1017415 CBP_HUMAN (52-326): 3.34e-09: 62.2: 11.64		CDC20_HUMAN (395-494): 7.34e-10: 63: 16.67