Interactor 1: SORT (Q99523)
Sortilin (100 kDa NT receptor) (Glycoprotein 95) (Gp95) (Neurotensin receptor 3) (NT3) (NTR3)
Gene: SORT1

Interactor 2: SORT (Q99523)
Sortilin (100 kDa NT receptor) (Glycoprotein 95) (Gp95) (Neurotensin receptor 3) (NT3) (NTR3)
Gene: SORT1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 1.00 0.853

The method score is based on:

Property Details
Experiments 19122660, 24128306, 25401472
Identification Methods surface plasmon resonance
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Sortilin-Vps10~Sortilin-Vps10, Sortilin_C~Sortilin-Vps10
Common GO terms GO:0001503 - ossification
GO:0005764 - lysosome
GO:0005765 - lysosomal membrane
GO:0005769 - early endosome
GO:0005789 - endoplasmic reticulum membrane
and 38 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 831
Hs

1 831
+ Hs
+ Hs
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024