HitPredict

Interactor 1: MPH6 (Q99547)
M-phase phosphoprotein 6
Gene: MPHOSPH6

Interactor 2: EXOS5 (Q9NQT4)
Exosome complex component RRP46 (Chronic myelogenous leukemia tumor antigen 28) (Exosome component 5) (Ribosomal RNA-processing protein 46) (p12B)
Gene: EXOSC5

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.696

Property	Details
Experiments	26496610, 28877463, 24981860, 33961781
Identification Methods	affinity chromatography technology, pull down, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000178 - exosome (RNase complex) GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 160 Hs			1 235
+	Hs
		1304448 MPH6_HUMAN (1-160): 1.95e-67: 203: 100.00		EXOS4_HUMAN (9-235): 1.12e-75: 230: 26.47
+	Hs
		110631 H3BNT4_HUMAN (19-160): 1.34e-58: 180: 100.00		EXOS4_HUMAN (9-235): 1.12e-75: 230: 26.47
+	Hs
		1284955 MPH6_HUMAN (1-160): 1.95e-67: 203: 100.00		EXOS8_HUMAN (4-234): 4.65e-59: 189: 19.26
+	Hs
		110632 H3BNT4_HUMAN (19-160): 1.34e-58: 180: 100.00		EXOS5_HUMAN (1-235): 2.29e-66: 206: 100.00
+	Hs
		1063758 MPH6_HUMAN (1-160): 1.95e-67: 203: 100.00		EXOS7_HUMAN (1-233): 2.23e-46: 157: 15.52
+	Hs
		1130047 MPH6_HUMAN (1-160): 1.95e-67: 203: 100.00		EXOS6_HUMAN (9-228): 2.79e-42: 146: 25.41