Interactor 1: MPP8 (Q99549)
M-phase phosphoprotein 8 (Two hybrid-associated protein 3 with RanBPM) (Twa3)
Gene: MPHOSPH8

Interactor 2: DNM3A (Q9Y6K1)
DNA (cytosine-5)-methyltransferase 3A (Dnmt3a) (EC 2.1.1.37) (Cysteine methyltransferase DNMT3A) (EC 2.1.1.-) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA)
Gene: DNMT3A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.53 1.00 0.734

The method score is based on:

Property Details
Experiments 22086334
Identification Methods unspecified method, affinity chromatography technology, x-ray crystallography
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Chromo~DNA_methylase
Common GO terms GO:0000792 - heterochromatin
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 1 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 860
Hs

1 912
+ Hs
+ Mm
+ Hs
+ Hs
+ Mm
+ Mm

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Last updated: 15 Jul 2024