HitPredict

Interactor 1: DNJC7 (Q99615)
DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2)
Gene: DNAJC7

Interactor 2: DNJB4 (Q9UDY4)
DnaJ homolog subfamily B member 4 (Heat shock 40 kDa protein 1 homolog) (HSP40 homolog) (Heat shock protein 40 homolog) (Human liver DnaJ-like protein)
Gene: DNAJB4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	DnaJ~DnaJ, DnaJ~DnaJ_C
Common GO terms	GO:0001671 - ATPase activator activity GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0051085 - chaperone cofactor-dependent protein refolding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 494 Hs			1 337
+	Hs
		279337 DNJC7_HUMAN (1-494): 2.58e-85: 273: 100.00		DNJB5_HUMAN (1-337): 1.41e-131: 380: 60.92
+	Hs
		636403 DNJC7_HUMAN (1-494): 2.58e-85: 273: 100.00		DNJB1_HUMAN (1-335): 7.26e-127: 368: 64.60
+	Hs
		243569 DNJC7_HUMAN (1-494): 2.58e-85: 273: 100.00		DNJA2_HUMAN (2-336): 8.37e-120: 353: 31.46
+	Hs
		681574 DNJC7_HUMAN (1-494): 2.58e-85: 273: 100.00		DNJA1_HUMAN (5-335): 9.73e-119: 349: 32.17
+	Hs
		1262159 DNJC7_HUMAN (1-494): 2.58e-85: 273: 100.00		DNJA4_HUMAN (5-336): 1.32e-116: 344: 31.12
+	Hs
		685080 STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49		DNJB4_HUMAN (1-337): 9.06e-140: 400: 100.00
+	Hs
		279292 DNJC3_HUMAN (14-289): 8.21e-26: 112: 17.83		DNJB5_HUMAN (1-337): 1.41e-131: 380: 60.92
+	Hs
		279279 STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49		DNJB5_HUMAN (1-337): 1.41e-131: 380: 60.92
+	Hs
		174480 OGT1_HUMAN (3-401): 1.62e-31: 130: 13.59		DNJA2_HUMAN (2-336): 8.37e-120: 353: 31.46
+	Hs
		174656 OGT1_HUMAN (3-401): 1.62e-31: 130: 13.59		DNJA1_HUMAN (5-335): 9.73e-119: 349: 32.17
+	Hs
		636254 STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49		DNJB1_HUMAN (1-335): 7.26e-127: 368: 64.60
+	Hs
		243387 DNJC3_HUMAN (14-289): 8.21e-26: 112: 17.83		DNJA2_HUMAN (2-336): 8.37e-120: 353: 31.46
+	Sc
		542103 CYC8_YEAST (28-406): 2.74e-32: 133: 15.07		MAS5_YEAST (5-336): 1.57e-111: 331: 30.60
+	Hs
		243309 STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49		DNJA2_HUMAN (2-336): 8.37e-120: 353: 31.46
+	Hs
		1028085 DNJC3_HUMAN (14-289): 8.21e-26: 112: 17.83		DNJA4_HUMAN (5-336): 1.32e-116: 344: 31.12
+	Hs
		681339 STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49		DNJA1_HUMAN (5-335): 9.73e-119: 349: 32.17
+	Dm
		247620 O61650_DROME (7-171): 4.01e-22: 101: 28.49		Q9VFV9_DROME (5-337): 1.16e-110: 329: 29.63
+	Hs
		1028120 DNJC3_HUMAN (14-289): 8.21e-26: 112: 17.83		DJB11_HUMAN (2-334): 6.07e-99: 298: 31.34
+	Hs
		1262557 DNJC7_HUMAN (1-494): 2.58e-85: 273: 100.00		DNJB3_HUMAN (4-108): 5.57e-28: 108: 55.56
+	Sc
		542102 CYC8_YEAST (28-406): 2.74e-32: 133: 15.07		SIS1_YEAST (6-334): 1.26e-53: 181: 33.69