HitPredict

Interactor 1: PHB2 (Q99623)
Prohibitin-2 (B-cell receptor-associated protein BAP37) (D-prohibitin) (Repressor of estrogen receptor activity)
Gene: PHB2

Interactor 2: MLP3B (Q9GZQ8)
Microtubule-associated proteins 1A/1B light chain 3B (Autophagy-related protein LC3 B) (Autophagy-related ubiquitin-like modifier LC3 B) (MAP1 light chain 3-like protein 2) (MAP1A/MAP1B light chain 3 B) (MAP1A/MAP1B LC3 B) (Microtubule-associated protein 1 light chain 3 beta)
Gene: MAP1LC3B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	31177901, 29416008, 20562859
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000423 - mitophagy GO:0005739 - mitochondrion
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 299 Hs			1 125
+	Hs
		1305258 PHB2_HUMAN (1-299): 2.46e-109: 320: 100.00		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50
+	Hs
		891280 PHB2_HUMAN (1-299): 2.46e-109: 320: 100.00		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Hs
		719122 PHB1_HUMAN (22-280): 1e-85: 259: 51.15		MLP3B_HUMAN (1-125): 8.28e-57: 173: 100.00
+	Hs
		719138 PHB1_HUMAN (22-280): 1e-85: 259: 51.15		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50
+	Hs
		718670 PHB1_HUMAN (22-280): 1e-85: 259: 51.15		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Hs
		719129 PHB1_HUMAN (22-280): 1e-85: 259: 51.15		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46