HitPredict

Interactor 1: CSN8 (Q99627)
COP9 signalosome complex subunit 8 (SGN8) (Signalosome subunit 8) (COP9 homolog) (hCOP9) (JAB1-containing signalosome subunit 8)
Gene: COPS8

Interactor 2: CSN7B (Q9H9Q2)
COP9 signalosome complex subunit 7b (SGN7b) (Signalosome subunit 7b) (JAB1-containing signalosome subunit 7b)
Gene: COPS7B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.925

The method score is based on:

Property Details
Experiments 27833851, 28514442, 33961781, 27173435, 9707402
Identification Methods affinity chromatography technology, biochemical, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CSN7a_helixI~CSN8_PSD8_EIF3K, CSN8_PSD8_EIF3K~PCI
Common GO terms GO:0000338 - protein deneddylation
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 3 others

more...
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 209
Hs

1 264
+ Hs
+ Hs
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024