HitPredict

Interactor 1: CHP1 (Q99653)
Calcineurin B homologous protein 1 (Calcineurin B-like protein) (Calcium-binding protein CHP) (Calcium-binding protein p22) (EF-hand calcium-binding domain-containing protein p22)
Gene: CHP1

Interactor 2: SL9A2 (Q9UBY0)
Sodium/hydrogen exchanger 2 (Na(+)/H(+) exchanger 2) (NHE-2) (Solute carrier family 9 member 2)
Gene: SLC9A2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	12576672
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	EF-hand_7~NEXCaM_BD
Common GO terms	GO:0005886 - plasma membrane GO:0015385 - sodium:proton antiporter activity GO:0051453 - regulation of intracellular pH
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 195 Hs			1 812
+	Rn
		822754 CHP1_RAT (1-195): 5.21e-50: 162: 98.97		SL9A2_RAT (1-812): 0: 808: 90.66
+	Rn
		822755 CHP2_RAT (1-194): 8.61e-45: 149: 61.03		SL9A2_RAT (1-812): 0: 808: 90.66
+	Hs
		212574 CHP2_HUMAN (1-194): 5.82e-48: 157: 61.03		SL9A2_HUMAN (1-812): 0: 791: 100.00
+	Hs
		1149580 CHP1_HUMAN (1-195): 2.96e-50: 162: 100.00		SL9A4_HUMAN (8-792): 0: 673: 53.33
+	Hs
		212570 CHP2_HUMAN (1-194): 5.82e-48: 157: 61.03		SL9A4_HUMAN (8-792): 0: 673: 53.33
+	Rn
		642818 CHP1_RAT (1-195): 5.21e-50: 162: 98.97		SL9A4_RAT (41-690): 0: 648: 62.16
+	Rn
		642819 CHP2_RAT (1-194): 8.61e-45: 149: 61.03		SL9A4_RAT (41-690): 0: 648: 62.16
+	Hs
		586063 CHP1_HUMAN (1-195): 2.96e-50: 162: 100.00		SL9A1_HUMAN (22-801): 0: 620: 45.51
+	Hs
		212564 CHP2_HUMAN (1-194): 5.82e-48: 157: 61.03		SL9A1_HUMAN (22-801): 0: 620: 45.51
+	Hs
		586058 CHP3_HUMAN (1-195): 1.08e-46: 154: 33.33		SL9A1_HUMAN (22-801): 0: 620: 45.51
+	Rn
		642812 CHP1_RAT (1-195): 5.21e-50: 162: 98.97		SL9A1_RAT (22-801): 0: 605: 45.20
+	Rn
		642813 CHP2_RAT (1-194): 8.61e-45: 149: 61.03		SL9A1_RAT (22-801): 0: 605: 45.20
+	Hs
		822764 CHP1_HUMAN (1-195): 2.96e-50: 162: 100.00		SL9A3_HUMAN (55-792): 0: 561: 40.08
+	Hs
		212565 CHP2_HUMAN (1-194): 5.82e-48: 157: 61.03		SL9A3_HUMAN (55-792): 0: 561: 40.08
+	Rn
		642815 CHP1_RAT (1-195): 5.21e-50: 162: 98.97		SL9A3_RAT (68-792): 0: 551: 39.33
+	Rn
		642816 CHP2_RAT (1-194): 8.61e-45: 149: 61.03		SL9A3_RAT (68-792): 0: 551: 39.33
+	Hs
		1060400 CHP1_HUMAN (1-195): 2.96e-50: 162: 100.00		SL9A5_HUMAN (68-697): 4.17e-166: 505: 43.37
+	Hs
		212568 CHP2_HUMAN (1-194): 5.82e-48: 157: 61.03		SL9A5_HUMAN (68-697): 4.17e-166: 505: 43.37
+	Rn
		895408 CHP1_RAT (1-195): 5.21e-50: 162: 98.97		SL9A5_RAT (44-700): 4.43e-164: 500: 41.97
+	Rn
		1194995 CHP2_RAT (1-194): 8.61e-45: 149: 61.03		SL9A5_RAT (44-700): 4.43e-164: 500: 41.97