HitPredict

Interactor 1: GPR21 (Q99679)
Probable G-protein coupled receptor 21
Gene: GPR21

Interactor 2: S12A4 (Q9UP95)
Solute carrier family 12 member 4 (Electroneutral potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (hKCC1)
Gene: SLC12A4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 349 Hs			1 1085
+	Hs
		1137085 OR2G6_HUMAN (7-322): 1.3e-62: 204: 17.87		S12A4_HUMAN (1-1085): 0: 1180: 100.00
+	Hs
		1137084 OR2G6_HUMAN (7-322): 1.3e-62: 204: 17.87		S12A6_HUMAN (7-1085): 0: 1111: 76.53
+	Hs
		1305575 GPR21_HUMAN (1-349): 2.76e-62: 204: 100.00		S12A6_HUMAN (7-1085): 0: 1111: 76.53
+	Hs
		781037 OPRD_HUMAN (16-347): 2.23e-62: 205: 18.05		S12A7_HUMAN (1-1085): 0: 1064: 69.05
+	Hs
		1305582 GPR21_HUMAN (1-349): 2.76e-62: 204: 100.00		S12A7_HUMAN (1-1085): 0: 1064: 69.05
+	Hs
		723286 APJ_HUMAN (30-346): 5.39e-61: 201: 14.88		S12A2_HUMAN (37-1085): 0: 754: 21.39
+	Hs
		1305564 GPR21_HUMAN (1-349): 2.76e-62: 204: 100.00		S12A9_HUMAN (116-911): 4.53e-144: 457: 26.11
+	Hs
		208469 OX2R_HUMAN (21-346): 1.28e-61: 205: 18.85		CTR3_HUMAN (162-603): 9.85e-80: 275: 13.32