Interactor 1: PITX2 (Q99697)
Pituitary homeobox 2 (ALL1-responsive protein ARP1) (Homeobox protein PITX2) (Paired-like homeodomain transcription factor 2) (RIEG bicoid-related homeobox transcription factor) (Solurshin)
Gene: PITX2

Interactor 2: TBX22 (Q9Y458)
T-box transcription factor TBX22 (T-box protein 22)
Gene: TBX22

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.665

The method score is based on:

Property Details
Experiments unassigned1304
Identification Methods two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Homeodomain~T-box
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 - nucleus
and 1 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 317
Hs

1 520
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Last updated: 15 Jul 2024