HitPredict

Interactor 1: METH (Q99707)
Methionine synthase (MS) (EC 2.1.1.13) (5-methyltetrahydrofolate--homocysteine methyltransferase) (Cobalamin-dependent methionine synthase) (Vitamin-B12 dependent methionine synthase)
Gene: MTR

Interactor 2: MTRR (Q9UBK8)
Methionine synthase reductase (MSR) (EC 1.16.1.8) (Aquacobalamin reductase) (AqCbl reductase)
Gene: MTRR

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.65 0.55 0.598

The method score is based on:

Property Details
Experiments 17477549, 16769880
Identification Methods pull down, x-ray crystallography, oxidoreductase assay
Interaction Type direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0009086 - methionine biosynthetic process
GO:0050667 - homocysteine metabolic process
Homologous interactions 0

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Last updated: 15 Jul 2024