Interactor 1: CTIP (Q99708)
DNA endonuclease RBBP8 (EC 3.1.-.-) (CtBP-interacting protein) (CtIP) (Retinoblastoma-binding protein 8) (RBBP-8) (Retinoblastoma-interacting protein and myosin-like) (RIM) (Sporulation in the absence of SPO11 protein 2 homolog) (SAE2)
Gene: RBBP8

Interactor 2: CTIP (Q99708)
DNA endonuclease RBBP8 (EC 3.1.-.-) (CtBP-interacting protein) (CtIP) (Retinoblastoma-binding protein 8) (RBBP-8) (Retinoblastoma-interacting protein and myosin-like) (RIM) (Sporulation in the absence of SPO11 protein 2 homolog) (SAE2)
Gene: RBBP8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 0.90 0.872

The method score is based on:

Property Details
Experiments 15084581, 17214969, 22544744, 25558984
Identification Methods affinity chromatography technology, pull down, biochemical, x-ray crystallography, molecular sieving, anti tag coimmunoprecipitation, light scattering
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CtIP_N~CtIP_N
Common GO terms GO:0000014 - single-stranded DNA endodeoxyribonuclease activity
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000724 - double-strand break repair via homologous recombination
GO:0001835 - blastocyst hatching
GO:0003684 - damaged DNA binding
and 17 others

more...

Homologous interactions 0

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Last updated: 15 Jul 2024