HitPredict

Interactor 1: SGMR1 (Q99720)
Sigma non-opioid intracellular receptor 1 (Aging-associated gene 8 protein) (SR31747-binding protein) (SR-BP) (Sigma 1-type opioid receptor) (SIG-1R) (Sigma1-receptor) (Sigma1R) (hSigmaR1)
Gene: SIGMAR1

Interactor 2: SGMR1 (Q99720)
Sigma non-opioid intracellular receptor 1 (Aging-associated gene 8 protein) (SR31747-binding protein) (SR-BP) (Sigma 1-type opioid receptor) (SIG-1R) (Sigma1-receptor) (Sigma1R) (hSigmaR1)
Gene: SIGMAR1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 1.00 0.820

The method score is based on:

Property Details
Experiments 27042935, 30291362
Identification Methods molecular sieving, light scattering, x-ray crystallography, comigration in non denaturing gel electrophoresis
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains ERG2_Sigma1R~ERG2_Sigma1R
Common GO terms GO:0004985 - G protein-coupled opioid receptor activity
GO:0005635 - nuclear envelope
GO:0005637 - nuclear inner membrane
GO:0005640 - nuclear outer membrane
GO:0005783 - endoplasmic reticulum
and 14 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 223
Hs

1 223
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024