Interactor 1: TS101 (Q99816)
Tumor susceptibility gene 101 protein (ESCRT-I complex subunit TSG101)
Gene: TSG101

Interactor 2: TS101 (Q99816)
Tumor susceptibility gene 101 protein (ESCRT-I complex subunit TSG101)
Gene: TSG101

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.953

The method score is based on:

Property Details
Experiments 25330247, 36949045, 16973552, 19542561, 12900394, 12663786, 19549727
Identification Methods protein complementation assay, two hybrid, unspecified method, pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains UEV~UEV, Vps23_core~Vps23_core
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000813 - ESCRT I complex
GO:0001558 - regulation of cell growth
GO:0003677 - DNA binding
GO:0003714 - transcription corepressor activity
and 45 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 390
Hs

1 390
+ Mm
+ At
+ At
+ At
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024