Interactor 1: TS101 (Q99816)
Tumor susceptibility gene 101 protein (ESCRT-I complex subunit TSG101)
Gene: TSG101

Interactor 2: VP37B (Q9H9H4)
Vacuolar protein sorting-associated protein 37B (hVps37B) (ESCRT-I complex subunit VPS37B)
Gene: VPS37B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.968

The method score is based on:

Property Details
Experiments 15240819, 15218037, 35271311, 27609421, 32296183, 19542561, 22405001, unassigned1304
Identification Methods pull down, two hybrid, affinity chromatography technology, unspecified method, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Mod_r~Vps23_core
Common GO terms GO:0000813 - ESCRT I complex
GO:0005737 - cytoplasm
GO:0005768 - endosome
GO:0005886 - plasma membrane
GO:0010008 - endosome membrane
and 11 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 390
Hs

1 285
+ Hs
+ Hs
+ Hs
+ Dm
+ Dm
+ Ce
+ At
+ At
+ At
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024