Interactor 1: TS101 (Q99816)
Tumor susceptibility gene 101 protein (ESCRT-I complex subunit TSG101)
Gene: TSG101

Interactor 2: VPS28 (Q9UK41)
Vacuolar protein sorting-associated protein 28 homolog (H-Vps28) (ESCRT-I complex subunit VPS28)
Gene: VPS28

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.989

The method score is based on:

Property Details
Experiments 26186194, 28514442, 26871637, 33961781, 35271311, 14505570, 21757351, 19060904, 25416956, 16189514, 27609421, 15218037, 32296183, 11134028, 12663786, 24284069, 31515488, unassigned1304
Identification Methods affinity chromatography technology, two hybrid, pull down, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation, two hybrid pooling approach, validated two hybrid
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains VPS28~Vps23_core
Common GO terms GO:0000813 - ESCRT I complex
GO:0005737 - cytoplasm
GO:0005768 - endosome
GO:0005769 - early endosome
GO:0005829 - cytosol
and 13 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 390
Hs

1 221
+ Dm
+ At
+ At
+ At
+ At
+ Dm
+ Sc
+ At
+ At

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Last updated: 15 Jul 2024