HitPredict

Interactor 1: TCPH (Q99832)
T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (Chaperonin containing T-complex polypeptide 1 subunit 7) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed]
Gene: CCT7

Interactor 2: TBL1Y (Q9BQ87)
F-box-like/WD repeat-containing protein TBL1Y (Transducin beta-like protein 1Y) (Transducin-beta-like protein 1, Y-linked)
Gene: TBL1Y

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0050821 - protein stabilization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 543 Hs			1 522
+	Hs
		826848 TCPG_HUMAN (1-541): 0: 577: 31.09		TBL1Y_HUMAN (1-522): 1.82e-157: 460: 100.00
+	Hs
		1306704 TCPH_HUMAN (1-543): 0: 647: 100.00		NLE1_HUMAN (13-344): 4.23e-58: 202: 12.17
+	Hs
		154696 TCPH_HUMAN (1-543): 0: 647: 100.00		GNB5_HUMAN (266-522): 5.47e-59: 202: 20.60
+	Hs
		826807 TCPG_HUMAN (1-541): 0: 577: 31.09		FBXW7_HUMAN (1-433): 1.43e-68: 235: 16.07
+	Hs
		903467 TCPH_HUMAN (1-543): 0: 647: 100.00		WDR5_HUMAN (13-303): 4.12e-41: 152: 12.93
+	Hs
		1202777 TCPH_HUMAN (1-543): 0: 647: 100.00		WDR5B_HUMAN (13-303): 8.6e-40: 148: 12.54
+	Hs
		154662 TCPG_HUMAN (1-541): 0: 577: 31.09		GNB5_HUMAN (266-522): 5.47e-59: 202: 20.60
+	Hs
		792942 TCPG_HUMAN (1-541): 0: 577: 31.09		LIS1_HUMAN (314-522): 1.08e-57: 198: 25.11
+	Hs
		154661 TCPE_HUMAN (3-527): 0: 557: 29.59		GNB5_HUMAN (266-522): 5.47e-59: 202: 20.60
+	Hs
		1240450 TCPH_HUMAN (1-543): 0: 647: 100.00		POC1A_HUMAN (13-238): 8.49e-21: 96.5: 10.44
+	Hs
		826601 TCPG_HUMAN (1-541): 0: 577: 31.09		WDR5_HUMAN (13-303): 4.12e-41: 152: 12.93
+	Hs
		826748 TCPG_HUMAN (1-541): 0: 577: 31.09		WDR5B_HUMAN (13-303): 8.6e-40: 148: 12.54
+	Hs
		283005 TCPH_HUMAN (1-543): 0: 647: 100.00		CIAO1_HUMAN (356-517): 9e-14: 74.3: 28.24
+	Hs
		826784 TCPG_HUMAN (1-541): 0: 577: 31.09		POC1B_HUMAN (13-250): 2.6e-26: 113: 11.65
+	Hs
		826772 TCPG_HUMAN (1-541): 0: 577: 31.09		POC1A_HUMAN (13-238): 8.49e-21: 96.5: 10.44
+	Sc
		744637 TCPH_YEAST (2-542): 0: 587: 62.45		TAF5_YEAST (175-390): 1.64e-14: 78.6: 25.11
+	Hs
		282850 TCPG_HUMAN (1-541): 0: 577: 31.09		CIAO1_HUMAN (356-517): 9e-14: 74.3: 28.24
+	Sc
		744632 TCPE_YEAST (2-526): 0: 568: 29.98		TAF5_YEAST (175-390): 1.64e-14: 78.6: 25.11
+	Hs
		282848 TCPE_HUMAN (3-527): 0: 557: 29.59		CIAO1_HUMAN (356-517): 9e-14: 74.3: 28.24
+	Cr
		65492 A8J7J2_CHLRE (3-521): 0: 567: 30.49		MUT11_CHLRE (160-442): 3.97e-10: 63.5: 22.79