HitPredict

Interactor 1: TCPH (Q99832)
T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (Chaperonin containing T-complex polypeptide 1 subunit 7) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed]
Gene: CCT7

Interactor 2: KTNB1 (Q9BVA0)
Katanin p80 WD40 repeat-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin)
Gene: KATNB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005874 - microtubule
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 543 Hs			1 655
+	Hs
		821392 TCPE_HUMAN (3-527): 0: 557: 29.59		KTNB1_HUMAN (4-655): 0: 559: 100.00
+	Hs
		197078 TCPH_HUMAN (1-543): 0: 647: 100.00		PRP4_HUMAN (4-301): 2.04e-83: 273: 24.38
+	Hs
		826784 TCPG_HUMAN (1-541): 0: 577: 31.09		POC1B_HUMAN (1-264): 9.89e-85: 276: 29.06
+	Hs
		196973 TCPG_HUMAN (1-541): 0: 577: 31.09		PRP4_HUMAN (4-301): 2.04e-83: 273: 24.38
+	Hs
		826807 TCPG_HUMAN (1-541): 0: 577: 31.09		FBXW7_HUMAN (48-344): 6.46e-76: 258: 22.52
+	Hs
		821326 TCPE_HUMAN (3-527): 0: 557: 29.59		POC1B_HUMAN (1-264): 9.89e-85: 276: 29.06
+	Hs
		196971 TCPE_HUMAN (3-527): 0: 557: 29.59		PRP4_HUMAN (4-301): 2.04e-83: 273: 24.38
+	Hs
		1306704 TCPH_HUMAN (1-543): 0: 647: 100.00		NLE1_HUMAN (180-470): 2.03e-43: 164: 15.39
+	Hs
		1240450 TCPH_HUMAN (1-543): 0: 647: 100.00		POC1A_HUMAN (1-91): 2.44e-19: 92.8: 21.98
+	Hs
		821437 TCPE_HUMAN (3-527): 0: 557: 29.59		NLE1_HUMAN (180-470): 2.03e-43: 164: 15.39
+	Hs
		903467 TCPH_HUMAN (1-543): 0: 647: 100.00		WDR5_HUMAN (267-467): 4.91e-13: 72.8: 8.33
+	Hs
		1202777 TCPH_HUMAN (1-543): 0: 647: 100.00		WDR5B_HUMAN (261-467): 3.81e-12: 70.1: 7.66
+	Hs
		792942 TCPG_HUMAN (1-541): 0: 577: 31.09		LIS1_HUMAN (227-420): 5.51e-27: 115: 14.29
+	Sc
		772946 TCPE_YEAST (2-526): 0: 568: 29.98		PRP46_YEAST (11-260): 4.89e-28: 119: 26.98
+	Hs
		821355 TCPE_HUMAN (3-527): 0: 557: 29.59		SNR40_HUMAN (181-384): 3.05e-30: 124: 17.62
+	Hs
		826772 TCPG_HUMAN (1-541): 0: 577: 31.09		POC1A_HUMAN (1-91): 2.44e-19: 92.8: 21.98
+	Hs
		821316 TCPE_HUMAN (3-527): 0: 557: 29.59		POC1A_HUMAN (1-91): 2.44e-19: 92.8: 21.98
+	Hs
		826601 TCPG_HUMAN (1-541): 0: 577: 31.09		WDR5_HUMAN (267-467): 4.91e-13: 72.8: 8.33
+	Hs
		826748 TCPG_HUMAN (1-541): 0: 577: 31.09		WDR5B_HUMAN (261-467): 3.81e-12: 70.1: 7.66
+	Hs
		821152 TCPE_HUMAN (3-527): 0: 557: 29.59		WDR5_HUMAN (267-467): 4.91e-13: 72.8: 8.33