HitPredict

Interactor 1: TCPH (Q99832)
T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (Chaperonin containing T-complex polypeptide 1 subunit 7) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed]
Gene: CCT7

Interactor 2: HDAC6 (Q9UBN7)
Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Protein deacetylase HDAC6) (EC 3.5.1.-) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-)
Gene: HDAC6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23703321
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005874 - microtubule
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 543 Hs			1 1215
+	Hs
		826927 TCPG_HUMAN (1-541): 0: 577: 31.09		HDAC6_HUMAN (1-1215): 0: 1435: 100.00
+	Hs
		821448 TCPE_HUMAN (3-527): 0: 557: 29.59		HDAC6_HUMAN (1-1215): 0: 1435: 100.00
+	Hs
		1038670 TCPH_HUMAN (1-543): 0: 647: 100.00		HDAC1_HUMAN (478-896): 4.05e-166: 503: 20.09
+	Mm
		945920 TCPH_MOUSE (1-543): 0: 656: 95.96		HDAC4_MOUSE (424-873): 9e-152: 485: 37.16
+	Hs
		1306741 TCPH_HUMAN (1-543): 0: 647: 100.00		HDAC5_HUMAN (33-471): 3.29e-145: 469: 32.48
+	Hs
		177367 TCPH_HUMAN (1-543): 0: 647: 100.00		HDAC3_HUMAN (479-890): 6.6e-146: 448: 18.29
+	Hs
		826651 TCPG_HUMAN (1-541): 0: 577: 31.09		HDAC1_HUMAN (478-896): 4.05e-166: 503: 20.09
+	Hs
		821200 TCPE_HUMAN (3-527): 0: 557: 29.59		HDAC1_HUMAN (478-896): 4.05e-166: 503: 20.09
+	Hs
		826803 TCPG_HUMAN (1-541): 0: 577: 31.09		HDAC2_HUMAN (78-489): 1.04e-157: 481: 21.02
+	Hs
		826942 TCPG_HUMAN (1-541): 0: 577: 31.09		HDAC5_HUMAN (33-471): 3.29e-145: 469: 32.48
+	Sc
		693035 TCPH_YEAST (2-542): 0: 587: 62.45		RPD3_YEAST (75-473): 1.1e-149: 458: 20.24
+	Hs
		821342 TCPE_HUMAN (3-527): 0: 557: 29.59		HDAC2_HUMAN (78-489): 1.04e-157: 481: 21.02
+	Mm
		945965 TCPE_MOUSE (3-527): 0: 550: 29.96		HDAC4_MOUSE (424-873): 9e-152: 485: 37.16
+	Hs
		821140 TCPE_HUMAN (3-527): 0: 557: 29.59		HDAC4_HUMAN (405-873): 1.97e-147: 474: 36.51
+	Sc
		693029 TCPE_YEAST (2-526): 0: 568: 29.98		RPD3_YEAST (75-473): 1.1e-149: 458: 20.24
+	Hs
		821464 TCPE_HUMAN (3-527): 0: 557: 29.59		HDAC5_HUMAN (33-471): 3.29e-145: 469: 32.48
+	Hs
		177233 TCPG_HUMAN (1-541): 0: 577: 31.09		HDAC3_HUMAN (479-890): 6.6e-146: 448: 18.29
+	Hs
		177231 TCPE_HUMAN (3-527): 0: 557: 29.59		HDAC3_HUMAN (479-890): 6.6e-146: 448: 18.29
+	Sc
		693017 TCPG_YEAST (2-527): 0: 546: 30.68		RPD3_YEAST (75-473): 1.1e-149: 458: 20.24
+	Hs
		177188 TCPA_HUMAN (2-533): 0: 544: 34.54		HDAC3_HUMAN (479-890): 6.6e-146: 448: 18.29