Interactor 1: MYD88 (Q99836)
Myeloid differentiation primary response protein MyD88
Gene: MYD88

Interactor 2: MYD88 (Q99836)
Myeloid differentiation primary response protein MyD88
Gene: MYD88

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.989

The method score is based on:

Property Details
Experiments 25416956, 21516116, 25910212, 27107012, 32296183, 31930677, 11544529, 9575168, 17548806, 21988832, 17228323, 16482509, 20966070, 21325272, 17258210, 22155231, 24316379, 29892012, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, pull down, anti tag coimmunoprecipitation, fluorescent resonance energy transfer, two hybrid array, mammalian protein protein interaction trap, split luciferase complementation, barcode fusion genetics two hybrid, validated two hybrid and 3 others

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Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Death~Death, TIR_2~TIR_2
Common GO terms GO:0002238 - response to molecule of fungal origin
GO:0002269 - leukocyte activation involved in inflammatory response
GO:0002283 - neutrophil activation involved in immune response
GO:0002755 - MyD88-dependent toll-like receptor signaling pathway
GO:0005121 - Toll binding
and 72 others

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Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 296
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Last updated: 15 Jul 2024