HitPredict

Interactor 1: MYD88 (Q99836)
Myeloid differentiation primary response protein MyD88
Gene: MYD88

Interactor 2: IL1AP (Q9NPH3)
Interleukin-1 receptor accessory protein (IL-1 receptor accessory protein) (IL-1RAcP) (EC 3.2.2.6) (Interleukin-1 receptor 3) (IL-1R-3) (IL-1R3)
Gene: IL1RAP

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 0.60 0.640

The method score is based on:

Property Details
Experiments 9374458, 15849357, 13679373
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005149 - interleukin-1 receptor binding
GO:0005886 - plasma membrane
GO:0032755 - positive regulation of interleukin-6 production
GO:0038172 - interleukin-33-mediated signaling pathway
GO:0045087 - innate immune response
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 296
Hs

1 570
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Last updated: 15 Jul 2024