Interactor 1: MYD88 (Q99836)
Myeloid differentiation primary response protein MyD88
Gene: MYD88

Interactor 2: TLR9 (Q9NR96)
Toll-like receptor 9 (CD antigen CD289)
Gene: TLR9

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 0.60 0.650

The method score is based on:

Property Details
Experiments 15107846, 21911421, 17417641
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, unspecified method
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002755 - MyD88-dependent toll-like receptor signaling pathway
GO:0005149 - interleukin-1 receptor binding
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0010008 - endosome membrane
and 12 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 296
Hs

1 1032
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024