Interactor 1: MYD88 (Q99836)
Myeloid differentiation primary response protein MyD88
Gene: MYD88
Interactor 2: IRAK4 (Q9NWZ3)
Interleukin-1 receptor-associated kinase 4 (IRAK-4) (EC 2.7.11.1) (Renal carcinoma antigen NY-REN-64)
Gene: IRAK4
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.98 | 0.60 | 0.767 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25416956, 25910212, 32296183, 11960013, 18221795, 22011580, 12538665, 17548806, 26871637, 12860405, 24735611, 20485341, 24316379, 15084582, 17486091, 12150927, 19167362, 20966070, 25502805, 31515488 and 1 others
more... |
| Identification Methods | two hybrid, affinity chromatography technology, protein complementation assay, molecular sieving, pull down, nuclear magnetic resonance, light scattering, anti tag coimmunoprecipitation, x-ray crystallography, split luciferase complementation and 4 others
more... |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0002755 - MyD88-dependent toll-like receptor signaling pathway GO:0005149 - interleukin-1 receptor binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol and 13 others more... |
| Homologous interactions | 10 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
