HitPredict

Interactor 1: MYD88 (Q99836)
Myeloid differentiation primary response protein MyD88
Gene: MYD88

Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 0.60 0.739

The method score is based on:

Property Details
Experiments 23831471, 31268348, 33052227, 22011580, 23381138, 31243359, 16517750
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002755 - MyD88-dependent toll-like receptor signaling pathway
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
and 15 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 296
Hs

1 522
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024