HitPredict

Interactor 1: MYD88 (Q99836)
Myeloid differentiation primary response protein MyD88
Gene: MYD88

Interactor 2: IRAK3 (Q9Y616)
Interleukin-1 receptor-associated kinase 3 (IRAK-3) (IL-1 receptor-associated kinase M) (IRAK-M) (Inactive IL-1 receptor-associated kinase 3)
Gene: IRAK3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.776

The method score is based on:

Property Details
Experiments 10383454, 12150927
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Death~Death
Common GO terms GO:0002755 - MyD88-dependent toll-like receptor signaling pathway
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0008063 - Toll signaling pathway
and 5 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 296
Hs

1 596
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024