HitPredict - High confidence protein-protein interactions

Method score	Annotation score	Interaction score
0.95	1.00	0.977

Method score

Annotation score

Interaction score

0.95

1.00

0.977

Property	Details
Experiments	25416956, 12737817, 16169070, 32296183, 17925405, 34728620, 16879614, 17426288, 23455924, unassigned1304
Identification Methods	two hybrid, x-ray crystallography, enzymatic study, affinity chromatography technology, pull down, two hybrid array, two hybrid prey pooling approach, validated two hybrid, two hybrid pooling approach, anti tag coimmunoprecipitation
Interaction Type	direct interaction, association, physical association

Property

Details

Experiments

25416956, 12737817, 16169070, 32296183, 17925405, 34728620, 16879614, 17426288, 23455924, unassigned1304

Identification Methods

two hybrid, x-ray crystallography, enzymatic study, affinity chromatography technology, pull down, two hybrid array, two hybrid prey pooling approach, validated two hybrid, two hybrid pooling approach, anti tag coimmunoprecipitation

Interaction Type

direct interaction, association, physical association

Property	Details
Interacting Pfam domains	Methyltransf_25~Methyltransf_25
Common GO terms	GO:0001701 - in utero embryonic development GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm and 36 others more... GO:0005765 - lysosomal membrane GO:0005829 - cytosol GO:0006479 - protein methylation GO:0007166 - cell surface receptor signaling pathway GO:0008168 - methyltransferase activity GO:0008170 - N-methyltransferase activity GO:0008276 - protein methyltransferase activity GO:0008284 - positive regulation of cell population proliferation GO:0008327 - methyl-CpG binding GO:0008380 - RNA splicing GO:0016274 - protein-arginine N-methyltransferase activity GO:0018216 - peptidyl-arginine methylation GO:0019082 - viral protein processing GO:0019899 - enzyme binding GO:0030510 - regulation of BMP signaling pathway GO:0031175 - neuron projection development GO:0034709 - methylosome GO:0035241 - protein-arginine omega-N monomethyltransferase activity GO:0035242 - protein-arginine omega-N asymmetric methyltransferase activity GO:0042054 - histone methyltransferase activity GO:0044020 - histone H4R3 methyltransferase activity GO:0045648 - positive regulation of erythrocyte differentiation GO:0045652 - regulation of megakaryocyte differentiation GO:0045653 - negative regulation of megakaryocyte differentiation GO:0045727 - positive regulation of translation GO:0046329 - negative regulation of JNK cascade GO:0046985 - positive regulation of hemoglobin biosynthetic process GO:0048273 - mitogen-activated protein kinase p38 binding GO:0048738 - cardiac muscle tissue development GO:0051260 - protein homooligomerization GO:0061431 - cellular response to methionine GO:0106080 - GATOR1 complex binding GO:1900745 - positive regulation of p38MAPK cascade GO:1904047 - S-adenosyl-L-methionine binding GO:1904263 - positive regulation of TORC1 signaling GO:1905168 - positive regulation of double-strand break repair via homologous recombination
Homologous interactions	16