HitPredict

Interactor 1: H2B1M (Q99879)
Histone H2B type 1-M (Histone H2B.e) (H2B/e)
Gene: H2BC14

Interactor 2: HDAC6 (Q9UBN7)
Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Protein deacetylase HDAC6) (EC 3.5.1.-) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-)
Gene: HDAC6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 1215
+	Hs
		241656 H2B1K_HUMAN (1-126): 1.42e-55: 171: 96.03		HDAC6_HUMAN (1-1215): 0: 1435: 100.00
+	Hs
		707778 H2B1B_HUMAN (1-126): 1.31e-55: 171: 96.83		HDAC6_HUMAN (1-1215): 0: 1435: 100.00
+	Hs
		886211 H2B1D_HUMAN (1-126): 2.86e-55: 170: 96.83		HDAC6_HUMAN (1-1215): 0: 1435: 100.00
+	Hs
		1307148 H2B1L_HUMAN (1-126): 4.1e-54: 167: 95.24		HDAC6_HUMAN (1-1215): 0: 1435: 100.00
+	Hs
		1038424 H2B2E_HUMAN (1-126): 6.59e-56: 171: 96.03		HDAC1_HUMAN (478-896): 4.05e-166: 503: 20.09
+	Hs
		707620 H2B1B_HUMAN (1-126): 1.31e-55: 171: 96.83		HDAC1_HUMAN (478-896): 4.05e-166: 503: 20.09
+	Hs
		918340 H2B1C_HUMAN (1-126): 1.23e-55: 171: 96.83		HDAC1_HUMAN (478-896): 4.05e-166: 503: 20.09
+	Hs
		1038530 H2B3B_HUMAN (1-126): 6.01e-53: 164: 92.86		HDAC1_HUMAN (478-896): 4.05e-166: 503: 20.09
+	Hs
		1038606 H2B1A_HUMAN (1-126): 4.77e-49: 154: 84.25		HDAC1_HUMAN (478-896): 4.05e-166: 503: 20.09
+	Hs
		1270408 H2B1M_HUMAN (1-126): 7.28e-57: 174: 100.00		HDAC2_HUMAN (78-489): 1.04e-157: 481: 21.02
+	Hs
		1087306 H2B2E_HUMAN (1-126): 6.59e-56: 171: 96.03		HDAC2_HUMAN (78-489): 1.04e-157: 481: 21.02
+	Hs
		707699 H2B1B_HUMAN (1-126): 1.31e-55: 171: 96.83		HDAC2_HUMAN (78-489): 1.04e-157: 481: 21.02
+	Hs
		1270409 H2B1L_HUMAN (1-126): 4.1e-54: 167: 95.24		HDAC2_HUMAN (78-489): 1.04e-157: 481: 21.02
+	Hs
		1231218 H2B3B_HUMAN (1-126): 6.01e-53: 164: 92.86		HDAC2_HUMAN (78-489): 1.04e-157: 481: 21.02
+	Hs
		241663 H2B1K_HUMAN (1-126): 1.42e-55: 171: 96.03		HDAC5_HUMAN (33-471): 3.29e-145: 469: 32.48
+	Hs
		1270361 H2B1A_HUMAN (1-126): 4.77e-49: 154: 84.25		HDAC2_HUMAN (78-489): 1.04e-157: 481: 21.02
+	Hs
		177352 H2B1A_HUMAN (1-126): 4.77e-49: 154: 84.25		HDAC3_HUMAN (479-890): 6.6e-146: 448: 18.29
+	Sc
		355966 H2B2_YEAST (3-125): 2.22e-41: 135: 69.92		HDA1_YEAST (80-456): 4.66e-148: 464: 33.17
+	Sc
		355583 H2B1_YEAST (3-125): 3.41e-37: 124: 69.92		HDA1_YEAST (80-456): 4.66e-148: 464: 33.17
+	Sc
		355401 H2B1_YEAST (3-125): 3.41e-37: 124: 69.92		RPD3_YEAST (75-473): 1.1e-149: 458: 20.24