HitPredict

Interactor 1: SH3G1 (Q99961)
Endophilin-A2 (EEN fusion partner of MLL) (Endophilin-2) (Extra eleven-nineteen leukemia fusion gene protein) (EEN) (SH3 domain protein 2B) (SH3 domain-containing GRB2-like protein 1)
Gene: SH3GL1

Interactor 2: DYN3 (Q9UQ16)
Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin)
Gene: DNM3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	10542231
Identification Methods	peptide array
Interaction Type	association

Property	Details
Interacting Pfam domains	PH~SH3_1
Common GO terms	GO:0005737 - cytoplasm GO:0098793 - presynapse GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 368 Hs			1 869
+	Hs
		1307464 SH3G3_HUMAN (1-368): 1.31e-87: 270: 66.30		DYN3_HUMAN (1-869): 0: 1080: 100.00
+	Hs
		1307442 SH3G2_HUMAN (1-368): 1.98e-84: 261: 68.75		DYN3_HUMAN (1-869): 0: 1080: 100.00
+	Hs
		840806 SH3G1_HUMAN (1-368): 7.32e-90: 276: 100.00		DYN2_HUMAN (1-869): 0: 1041: 79.21
+	Hs
		840808 SH3G3_HUMAN (1-368): 1.31e-87: 270: 66.30		DYN2_HUMAN (1-869): 0: 1041: 79.21
+	Hs
		983404 SH3G1_HUMAN (1-368): 7.32e-90: 276: 100.00		DYN1_HUMAN (1-852): 0: 1035: 78.56
+	Mm
		760453 SH3G1_MOUSE (1-368): 7.42e-89: 273: 94.02		DYN1_MOUSE (1-847): 0: 1035: 78.90
+	Mm
		760455 SH3G3_MOUSE (1-367): 8.72e-87: 267: 63.76		DYN1_MOUSE (1-847): 0: 1035: 78.90
+	Hs
		840807 SH3G2_HUMAN (1-368): 1.98e-84: 261: 68.75		DYN2_HUMAN (1-869): 0: 1041: 79.21
+	Rn
		193636 SH3G1_RAT (1-368): 5.26e-88: 271: 92.94		DYN1_RAT (1-852): 0: 1028: 78.22
+	Hs
		983405 SH3G2_HUMAN (1-368): 1.98e-84: 261: 68.75		DYN1_HUMAN (1-852): 0: 1035: 78.56
+	Mm
		760454 SH3G2_MOUSE (1-368): 8.98e-84: 260: 69.02		DYN1_MOUSE (1-847): 0: 1035: 78.90
+	Rn
		192351 SH3G2_RAT (1-368): 2.02e-84: 261: 68.48		DYN1_RAT (1-852): 0: 1028: 78.22
+	Rn
		192355 SH3G3_RAT (1-368): 2.22e-84: 261: 62.77		DYN1_RAT (1-852): 0: 1028: 78.22
+	Mm
		760467 SHLB1_MOUSE (10-363): 3.6e-69: 223: 25.00		DYN1_MOUSE (1-847): 0: 1035: 78.90
+	Dm
		649303 SH3G3_DROME (1-367): 1.34e-75: 239: 48.10		DYN_DROME (6-861): 0: 974: 64.46
+	Hs
		983392 NOSTN_HUMAN (5-364): 1.09e-39: 149: 17.34		DYN1_HUMAN (1-852): 0: 1035: 78.56
+	Mm
		760473 SRC8_MOUSE (85-362): 7.3e-38: 144: 13.62		DYN2_MOUSE (1-869): 0: 1038: 79.21
+	Ce
		70029 SH3GH_CAEEL (1-366): 1.14e-70: 227: 44.76		DYN1_CAEEL (3-815): 0: 947: 62.09
+	Hs
		128631 SH3G1_HUMAN (1-368): 7.32e-90: 276: 100.00		DNM1L_HUMAN (6-750): 0: 788: 38.25
+	Hs
		128646 SHLB2_HUMAN (10-363): 1.2e-58: 196: 22.39		DNM1L_HUMAN (6-750): 0: 788: 38.25