Interactor 1: TIRAP (Q99JY1)
Toll/interleukin-1 receptor domain-containing adapter protein (TIR domain-containing adapter protein) (Adaptor protein Wyatt) (MyD88 adapter-like protein)
Gene: TIRAP

Interactor 2: TLR4 (Q9QUK6)
Toll-like receptor 4 (CD antigen CD284)
Gene: TLR4

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.481

The method score is based on:

Property Details
Experiments 19378012
Identification Methods protein complementation assay
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0006954 - inflammatory response
GO:0009617 - response to bacterium
GO:0030890 - positive regulation of B cell proliferation
GO:0032496 - response to lipopolysaccharide
and 13 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 241
Mm

1 835
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024